In recent human progress, more and more people recognize the benefits and contribution of cannabinoids in the medical field. These cannabinoids or phytocannabinoids are chemical compounds found in a strain of Cannabis sativa or more commonly known as Hemp.
While our own body naturally produces cannabinoids called Endocannabinoids, the cannabinoids found in Hemp plants mimic the functions of endocannabinoids that are important in different functions of our body.
There are over a hundred cannabinoids that have been extracted and identified from the Cannabis plant. Cannabigerol or CBG was first discovered in 1964 and became known to be the “template or stem cell of cannabinoids”. Many of cannabinoids and other minor compounds derived from CBG. THC and CBD are the most common cannabinoids. THC or delta-9-tetrahydrocannabinol is found to be the most abundant cannabinoid, it is known to have psychoactive effects. CBD or cannabidiol is known for its many medicinal benefits. Since both CBG and CBD are known to have non-psychotropic components, consumption of these cannabinoids will not affect and alter the users’ brain function. While CBG is a lesser-known cannabinoid, CBG itself has a lot of benefits to offer on its own.
CBG is proven to be a potent anti-bacterial. In 2008, a study on cannabinoids such as CBG has demonstrated its great effect against methicillin-resistant Staphylococcus aureus (MRSA). MRSA is responsible for causing infections in our body. In this study, CBG has shown its capacity to combat bacteria that are resistant to common antibio tics.
Glaucoma is generally caused by the imbalance of internal fluid in the eyes which causes pressure to build-up on the blood vessels. A study in 1984 shows significant reduction of ocular pressure after using CBG. While other cannabinoids in the study also displayed similar effects, CBG did not cause skin redness caused by hyperemia.
Diseases like Huntington’s and Parkinson’s are caused by the loss of function or death of nerve cells in the brain. The effect of using CBG for the treatment of neurodegenerative diseases was tested in a study done in 2015. The study shows CBG exhibiting neuroprotective properties by normalizing characteristics caused by abnormal genes that are linked to the deterioration of the brain nerve cells.
Keratin is one of the most important proteins found in our skin. It functions as a barrier and protects our body from the external surroundings. In 2007, results in a study show that cannabinoids such as CBG promote the reproduction of keratinocyte. Keratinocytes are important in the body as it is responsible for the production of keratin in the skin. In recent years, CBG oil containing a high concentration of CBG is becoming popular as an alternative for treating skin conditions.
Inflammatory Bowel Diseases or more commonly known as IDB has no known cure yet. Symptoms of IDB may be different to each person, often it would include abdominal pain, cramping, diarrhea, and ulcer. In a 2008 review, there are more than 50 studies made on cannabinoids and its effects on intestinal inflammation. These studies show that CBG has the most positive effect compared to other studied cannabinoids. In a journal from 2015, CBG was found to effectively reduce the uncomfortable symptoms of IDB.
CBG helps increase the level of anandamides in the brain. Anandamides are neurotransmitters that help maintain homeostasis in the body. It acts as a GABA uptake inhibitor that helps reduce anxiety and relaxes the body. It also counteracts the negative effects caused by THC like short-term memory deficits and associated anxiety.
A manuscript was published in 2015 that tested the effects of cannabinoids in cancer cells and tumors. This study included non-psychoactive cannabinoids such as cannabidiol (CBD), cannabichromene (CBC), cannabinol (CBN), and cannabigerol (CBG). These cannabinoids proved that they have the capacity to slow down the growth of cancer cells and tumors such as prostate carcinoma, breast carcinoma, and gastric adenocarcinoma.
Cannabigerol is meant to be converted into other cannabinoids, for this reason, it is much harder to extract large amounts of CBG and study it. But the future of CBG is bright, while it is not much explored like the other cannabinoids, CBG offers an abundance of promising potentials that will help reduce symptoms and fight diseases in the medical field, positively affecting the lives of people.
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